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Drug prioritization using the semantic properties of a knowledge graph
Compounds that are candidates for drug repurposing can be ranked by leveraging knowledge available in the biomedical literature and databases. This knowledge, spread across a variety of sources, can be integrated within a knowledge graph, which thereby comprehensively describes known relationships b...
Autores principales: | Malas, Tareq B., Vlietstra, Wytze J., Kudrin, Roman, Starikov, Sergey, Charrout, Mohammed, Roos, Marco, Peters, Dorien J. M., Kors, Jan A., Vos, Rein, ‘t Hoen, Peter A. C., van Mulligen, Erik M., Hettne, Kristina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472420/ https://www.ncbi.nlm.nih.gov/pubmed/31000794 http://dx.doi.org/10.1038/s41598-019-42806-6 |
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