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Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis

PURPOSE: To clinically use the UCSF500, a pancancer, next-generation sequencing assay in uveal melanoma (UM) and to correlate results with gene expression profiling (GEP) and predictive factors for metastasis. METHODS: Cohort study. Tumor samples of adult UM patients were analyzed with the UCSF500 a...

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Detalles Bibliográficos
Autores principales: Afshar, Armin R., Damato, Bertil E., Stewart, Jay M., Zablotska, Lydia B., Roy, Ritu, Olshen, Adam B., Joseph, Nancy M., Bastian, Boris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472431/
https://www.ncbi.nlm.nih.gov/pubmed/31024753
http://dx.doi.org/10.1167/tvst.8.2.18