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Seeing and sensing single G protein-coupled receptors by atomic force microscopy

G protein-coupled receptors (GPCRs) relay extracellular information across cell membranes through a continuum of conformations that are not always captured in structures. Hence, complementary approaches are required to quantify the physical and chemical properties of the dynamic conformations linkin...

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Detalles Bibliográficos
Autores principales: Sapra, K Tanuj, Spoerri, Patrizia M, Engel, Andreas, Alsteens, David, Müller, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472649/
https://www.ncbi.nlm.nih.gov/pubmed/30412846
http://dx.doi.org/10.1016/j.ceb.2018.10.006