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RNA sequencing of intestinal mucosa reveals novel pathways functionally linked to celiac disease pathogenesis

BACKGROUND & AIMS: The early steps in the pathophysiology of celiac disease (CD) leading to loss of tolerance to gluten are poorly described. Our aim was to use RNA sequencing of duodenal biopsies in patients with active CD, CD in remission, and non-CD controls to gain insight into CD pathophysi...

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Detalles Bibliográficos
Autores principales: Leonard, Maureen M., Bai, Yu, Serena, Gloria, Nickerson, Kourtney P., Camhi, Stephanie, Sturgeon, Craig, Yan, Shu, Fiorentino, Maria R., Katz, Aubrey, Nath, Barbara, Richter, James, Sleeman, Matthew, Gurer, Cagan, Fasano, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472737/
https://www.ncbi.nlm.nih.gov/pubmed/30998704
http://dx.doi.org/10.1371/journal.pone.0215132