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Identification of the minimum region of flatfish myostatin propeptide (Pep45-65) for myostatin inhibition and its potential to enhance muscle growth and performance in animals

Myostatin (MSTN) negatively regulates skeletal muscle growth, and its activity is inhibited by the binding of MSTN propeptide (MSTNpro), the N-terminal domain of proMSTN that is proteolytically cleaved from the proMSTN. Partial sequences from the N-terminal side of MSTNpro have shown to be sufficien...

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Detalles Bibliográficos
Autores principales: Kim, Jeong Hwan, Kim, Jeong Han, Sutikno, Lisa Andriani, Lee, Sang Beum, Jin, Deuk-Hee, Hong, Yong-Ki, Kim, Yong Soo, Jin, Hyung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472743/
https://www.ncbi.nlm.nih.gov/pubmed/30998775
http://dx.doi.org/10.1371/journal.pone.0215298