A robust data-driven genomic signature for idiopathic pulmonary fibrosis with applications for translational model selection

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease affecting ~5 million people globally. We have constructed an accurate model of IPF disease status using elastic net regularized regression on clinical gene expression data. Leveraging whole transcriptome microarray data fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ammar, Ron, Sivakumar, Pitchumani, Jarai, Gabor, Thompson, John Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472794/
https://www.ncbi.nlm.nih.gov/pubmed/30998768
http://dx.doi.org/10.1371/journal.pone.0215565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472794/
https://www.ncbi.nlm.nih.gov/pubmed/30998768
http://dx.doi.org/10.1371/journal.pone.0215565

Ejemplares similares