A robust data-driven genomic signature for idiopathic pulmonary fibrosis with applications for translational model selection

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease affecting ~5 million people globally. We have constructed an accurate model of IPF disease status using elastic net regularized regression on clinical gene expression data. Leveraging whole transcriptome microarray data fr...

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Detalles Bibliográficos
Autores principales: Ammar, Ron, Sivakumar, Pitchumani, Jarai, Gabor, Thompson, John Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472794/
https://www.ncbi.nlm.nih.gov/pubmed/30998768
http://dx.doi.org/10.1371/journal.pone.0215565

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