In silico analysis of the V66M variant of human BDNF in psychiatric disorders: An approach to precision medicine

Brain-derived neurotrophic factor (BDNF) plays an important role in neurogenesis and synapse formation. The V66M is the most prevalent BDNF mutation in humans and impairs the function and distribution of BDNF. This mutation is related to several psychiatric disorders. The pro-region of BDNF, particu...

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Detalles Bibliográficos
Autores principales: De Oliveira, Clara Carolina Silva, Pereira, Gabriel Rodrigues Coutinho, De Alcantara, Jamile Yvis Santos, Antunes, Deborah, Caffarena, Ernesto Raul, De Mesquita, Joelma Freire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472887/
https://www.ncbi.nlm.nih.gov/pubmed/30998730
http://dx.doi.org/10.1371/journal.pone.0215508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472887/
https://www.ncbi.nlm.nih.gov/pubmed/30998730
http://dx.doi.org/10.1371/journal.pone.0215508

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