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Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56

Breast cancer ranks no. 1 in women cancer worldwide, while 60–70% are estrogen receptor alpha positive. The estrogen selective modulators, such as tamoxifen, become the effective drugs for controlling ER alpha breast cancer progression. However, tamoxifen resistance will develop during long-time tre...

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Detalles Bibliográficos
Autores principales: Xue, Min, Zhang, Kai, Mu, Kun, Xu, Juntao, Yang, Huijie, Liu, Yun, Wang, Beibei, Wang, Zhonghao, Li, Zhongbo, Kong, Qiong, Li, Xiumin, Wang, Hui, Zhu, Jian, Zhuang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473003/
https://www.ncbi.nlm.nih.gov/pubmed/31000690
http://dx.doi.org/10.1038/s41389-019-0139-x