Ranking Hits From Saturation Transfer Difference Nuclear Magnetic Resonance–Based Fragment Screening

Fragment-based screening is an established route to identify low-molecular-weight molecules to generate high-affinity inhibitors in drug discovery. The affinities of these early hits from fragment screenings require a highly sensitive biophysical screening technique. Saturation transfer difference (...

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Detalles Bibliográficos
Autores principales: Aretz, Jonas, Rademacher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473174/
https://www.ncbi.nlm.nih.gov/pubmed/31032246
http://dx.doi.org/10.3389/fchem.2019.00215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473174/
https://www.ncbi.nlm.nih.gov/pubmed/31032246
http://dx.doi.org/10.3389/fchem.2019.00215

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