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Upregulation of PITX2 Promotes Letrozole Resistance Via Transcriptional Activation of IFITM1 Signaling in Breast Cancer Cells

PURPOSE: Although the interferon α (IFNα) signaling and the paired-like homeodomain transcription factor 2 (PITX2) have both been implicated in the progression of breast cancer (BCa), it remains obscure whether these two pathways act in a coordinated manner. We therefore aimed to elucidate the expre...

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Detalles Bibliográficos
Autores principales: Xu, Ying-ying, Yu, Hai-ru, Sun, Jia-yi, Zhao, Zhao, Li, Shuang, Zhang, Xin-feng, Liao, Zhi-xuan, Cui, Ming-ke, Li, Juan, Li, Chan, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473270/
https://www.ncbi.nlm.nih.gov/pubmed/30025446
http://dx.doi.org/10.4143/crt.2018.100