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Disulfiram, a Re-positioned Aldehyde Dehydrogenase Inhibitor, Enhances Radiosensitivity of Human Glioblastoma Cells In Vitro

PURPOSE: Glioblastoma, the most common brain tumor in adults, has poor prognosis. The purpose of this study was to determine the effect of disulfiram (DSF), an aldehyde dehydrogenase inhibitor, on in vitro radiosensitivity of glioblastoma cells with different methylation status of O(6)-methylguanine...

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Detalles Bibliográficos
Autores principales: Koh, Hyeon Kang, Seo, Soo Yeon, Kim, Jin Ho, Kim, Hak Jae, Chie, Eui Kyu, Kim, Seung-Ki, Kim, Il Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473295/
https://www.ncbi.nlm.nih.gov/pubmed/30121967
http://dx.doi.org/10.4143/crt.2018.249