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HDAC2 Inhibitor Valproic Acid Increases Radiation Sensitivity of Drug-Resistant Melanoma Cells

Resistance to anticancer drugs limits the effectiveness of chemotherapy in cancers. Melanoma cell lines B16F10C and A375C (parental) and B16F10R and A375R (drug-resistant sublines) were used to test radiation sensitization potential of valproic acid (VPA), an inhibitor of Histone deacetylase2 (HDAC2...

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Detalles Bibliográficos
Autores principales: Kalal, Bhuvanesh Sukhlal, Pai, Vinitha Ramanath, Behera, Santosh Kumar, Somashekarappa, Hiriyur Mallaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473314/
https://www.ncbi.nlm.nih.gov/pubmed/30909413
http://dx.doi.org/10.3390/medsci7030051