The Membrane-Active Phytopeptide Cycloviolacin O2 Simultaneously Targets HIV-1-infected Cells and Infectious Viral Particles to Potentiate the Efficacy of Antiretroviral Drugs

Background: Novel strategies to increase the efficacy of antiretroviral (ARV) drugs will be of crucial importance. We hypothesize that membranes of HIV-1-infected cells and enveloped HIV-1 particles may be preferentially targeted by the phytopeptide, cycloviolacin O2 (CyO2) to significantly enhance...

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Detalles Bibliográficos
Autores principales: Gerlach, Samantha L., Chandra, Partha K., Roy, Upal, Gunasekera, Sunithi, Göransson, Ulf, Wimley, William C., Braun, Stephen E., Mondal, Debasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473583/
https://www.ncbi.nlm.nih.gov/pubmed/30823453
http://dx.doi.org/10.3390/medicines6010033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473583/
https://www.ncbi.nlm.nih.gov/pubmed/30823453
http://dx.doi.org/10.3390/medicines6010033

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