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Loss of SMYD1 Results in Perinatal Lethality via Selective Defects within Myotonic Muscle Descendants

SET and MYND Domain 1 (SMYD1) is a cardiac and skeletal muscle-specific, histone methyl transferase that is critical for both embryonic and adult heart development and function in both mice and men. We report here that skeletal muscle-specific, myogenin (myoG)-Cre-mediated conditional knockout (CKO)...

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Detalles Bibliográficos
Autores principales: Rasmussen, Tara L., Tucker, Haley O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473627/
https://www.ncbi.nlm.nih.gov/pubmed/30577454
http://dx.doi.org/10.3390/diseases7010001