The Antidepressant Mirtazapine Inhibits Hepatic Innate Immune Networks to Attenuate Immune-Mediated Liver Injury in Mice

Activation of the innate immune system, including tissue macrophages and associated neutrophil infiltration, is an important driver of subsequent adaptive immune responses in many autoimmune diseases, including autoimmune hepatitis (AIH). The antidepressant mirtazapine has a unique complex pharmacol...

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Detalles Bibliográficos
Autores principales: Almishri, Wagdi, Shaheen, Abdel Aziz, Sharkey, Keith A., Swain, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474187/
https://www.ncbi.nlm.nih.gov/pubmed/31031775
http://dx.doi.org/10.3389/fimmu.2019.00803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474187/
https://www.ncbi.nlm.nih.gov/pubmed/31031775
http://dx.doi.org/10.3389/fimmu.2019.00803

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