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Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach

BACKGROUND: TNM8 staging for oropharyngeal squamous cell carcinomas (OPSCC) surrogates p16 immunohistochemistry for HPV testing. Patients with p16+ OPSCC may lack HPV aetiology. Here, we evaluate the suitability of TNM8 staging for guiding prognosis in such patients. METHODS: HPV status was ascertai...

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Detalles Bibliográficos
Autores principales: Craig, Stephanie G., Anderson, Lesley A., Schache, Andrew G., Moran, Michael, Graham, Laura, Currie, Keith, Rooney, Keith, Robinson, Max, Upile, Navdeep S., Brooker, Rachel, Mesri, Mina, Bingham, Victoria, McQuaid, Stephen, Jones, Terry, McCance, Dennis J., Salto-Tellez, Manuel, McDade, Simon S., James, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474272/
https://www.ncbi.nlm.nih.gov/pubmed/30890775
http://dx.doi.org/10.1038/s41416-019-0414-9