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Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach
BACKGROUND: TNM8 staging for oropharyngeal squamous cell carcinomas (OPSCC) surrogates p16 immunohistochemistry for HPV testing. Patients with p16+ OPSCC may lack HPV aetiology. Here, we evaluate the suitability of TNM8 staging for guiding prognosis in such patients. METHODS: HPV status was ascertai...
Autores principales: | Craig, Stephanie G., Anderson, Lesley A., Schache, Andrew G., Moran, Michael, Graham, Laura, Currie, Keith, Rooney, Keith, Robinson, Max, Upile, Navdeep S., Brooker, Rachel, Mesri, Mina, Bingham, Victoria, McQuaid, Stephen, Jones, Terry, McCance, Dennis J., Salto-Tellez, Manuel, McDade, Simon S., James, Jacqueline A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474272/ https://www.ncbi.nlm.nih.gov/pubmed/30890775 http://dx.doi.org/10.1038/s41416-019-0414-9 |
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