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The Signal Transducer and Activator of Transcription 5B (STAT5B) Gene Promotes Proliferation and Drug Resistance of Human Mantle Cell Lymphoma Cells by Activating the Akt Signaling Pathway

BACKGROUND: Mantle cell lymphoma (MCL) is a high-grade B-cell lymphoma with poor prognosis. Fludarabine is used alone or in combination for relapsed and advanced-stage MCL. The expression of the signal transducer and activator of transcription 5B (STAT5B) gene is associated with tumorigenesis in sol...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjun, Liang, Xiping, Gong, Yi, Xiao, Chunyan, Guo, Bingling, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474296/
https://www.ncbi.nlm.nih.gov/pubmed/30964854
http://dx.doi.org/10.12659/MSM.914934