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Copper transporter 1 (CTR1) expression by mouse testicular germ cells, but not Sertoli cells, is essential for functional spermatogenesis

An imbalance in copper (Cu) tissue homeostasis has a degenerative effect on spermatogenesis and male fertility. The high-affinity Cu transporter 1 (CTR1; SLC31A1) is the major protein responsible for Cu acquisition in eukaryotes and is highly expressed in mouse testes. Studies on yeast and Drosophil...

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Detalles Bibliográficos
Autores principales: Ghaffari, Rashin, Di Bona, Kristin R., Riley, Christopher L., Richburg, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474593/
https://www.ncbi.nlm.nih.gov/pubmed/31002737
http://dx.doi.org/10.1371/journal.pone.0215522