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Bioactive sphingolipid profile in a xenograft mouse model of head and neck squamous cell carcinoma

The purpose of this study was to determine the profile of bioactive sphingolipids in xenograft mouse tissues of head and neck squamous cell carcinoma. We utilized UHPLC-MS/MS to determine the profile of full set of ceramides, sphingosine, and sphingosine 1-phosphate in this xenograft mouse model. Th...

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Detalles Bibliográficos
Autores principales: Bai, Aiping, Liu, Xiang, Bielawski, Jacek, Hannun, Yusuf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474618/
https://www.ncbi.nlm.nih.gov/pubmed/31002723
http://dx.doi.org/10.1371/journal.pone.0215770