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A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle

Recombinant herpesvirus vaccine vectors offer distinct advantages in next-generation vaccine development, primarily due to the ability to establish persistent infections to provide sustainable antigen responses in the host. Recombinant bovine herpesvirus-4 (BoHV-4) has been previously shown to elici...

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Detalles Bibliográficos
Autores principales: Williams, Laura B. A., Fry, Lindsay M., Herndon, David R., Franceschi, Valentina, Schneider, David A., Donofrio, Gaetano, Knowles, Donald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474629/
https://www.ncbi.nlm.nih.gov/pubmed/31002724
http://dx.doi.org/10.1371/journal.pone.0215605