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Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway

Tubule-interstitial injury (TII) is a critical step in the progression of renal disease. It has been proposed that changes in proximal tubule (PT) albumin endocytosis plays an important role in the development of TII. Some reports have shown protective effects of lithium on kidney injury animal mode...

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Detalles Bibliográficos
Autores principales: Teixeira, Douglas E., Peruchetti, Diogo B., Silva, Leandro S., Silva-Aguiar, Rodrigo P., Oquendo, Morgana B., Silva-Filho, João Luiz, Takiya, Christina M., Leal-Cardoso, José Henrique, Pinheiro, Ana Acacia S., Caruso-Neves, Celso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474631/
https://www.ncbi.nlm.nih.gov/pubmed/31002704
http://dx.doi.org/10.1371/journal.pone.0215871