Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice

NOD-like receptor protein 3 (NLRP3) inflammasome activation triggers caspase-1 activation-induced maturation of interleukin (IL)-1β and IL-18 and therefore is important for the development of the host defense against various RNA viral diseases. However, the implication of this protein complex in hum...

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Detalles Bibliográficos
Autores principales: Lê, Vuong B., Dubois, Julia, Couture, Christian, Cavanagh, Marie-Hélène, Uyar, Olus, Pizzorno, Andres, Rosa-Calatrava, Manuel, Hamelin, Marie-Ève, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474638/
https://www.ncbi.nlm.nih.gov/pubmed/30964929
http://dx.doi.org/10.1371/journal.ppat.1007689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474638/
https://www.ncbi.nlm.nih.gov/pubmed/30964929
http://dx.doi.org/10.1371/journal.ppat.1007689

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