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Quantifying in situ adaptive immune cell cognate interactions in humans

Two-photon excitation microscopy (TPEM) has revolutionized our understanding of adaptive immunity. However, TPEM usually requires animal models and is not amenable to the study of human disease. Recognition of antigen by T cells requires cell contact and is associated with changes in T cell shape. W...

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Detalles Bibliográficos
Autores principales: Liarski, Vladimir M., Sibley, Adam, van Panhuys, Nicholas, Ai, Junting, Chang, Anthony, Kennedy, Domenick, Merolle, Maria, Germain, Ronald N., Giger, Maryellen L., Clark, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474677/
https://www.ncbi.nlm.nih.gov/pubmed/30778242
http://dx.doi.org/10.1038/s41590-019-0315-3