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Quantifying in situ adaptive immune cell cognate interactions in humans
Two-photon excitation microscopy (TPEM) has revolutionized our understanding of adaptive immunity. However, TPEM usually requires animal models and is not amenable to the study of human disease. Recognition of antigen by T cells requires cell contact and is associated with changes in T cell shape. W...
Autores principales: | Liarski, Vladimir M., Sibley, Adam, van Panhuys, Nicholas, Ai, Junting, Chang, Anthony, Kennedy, Domenick, Merolle, Maria, Germain, Ronald N., Giger, Maryellen L., Clark, Marcus R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474677/ https://www.ncbi.nlm.nih.gov/pubmed/30778242 http://dx.doi.org/10.1038/s41590-019-0315-3 |
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