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DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage

BACKGROUND: Recent computational advances in ancient DNA research have opened access to the detection of ancient DNA methylation footprints at the genome-wide scale. The most commonly used approach infers the methylation state of a given genomic region on the basis of the amount of nucleotide mis-in...

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Detalles Bibliográficos
Autores principales: Hanghøj, Kristian, Renaud, Gabriel, Albrechtsen, Anders, Orlando, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474913/
https://www.ncbi.nlm.nih.gov/pubmed/31004132
http://dx.doi.org/10.1093/gigascience/giz025