Influence of 2‐Methoxyestradiol and Sex on Hypoxia‐Induced Pulmonary Hypertension and Hypoxia‐Inducible Factor‐1‐α

BACKGROUND: Women are at greater risk of developing pulmonary arterial hypertension, with estrogen and its downstream metabolites playing a potential role in the pathogenesis of the disease. Hypoxia‐inducible factor‐1‐α (HIF1α) is a pro‐proliferative mediator and may be involved in the development o...

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Detalles Bibliográficos
Autores principales: Docherty, Craig K., Nilsen, Margaret, MacLean, Margaret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474940/
https://www.ncbi.nlm.nih.gov/pubmed/30819028
http://dx.doi.org/10.1161/JAHA.118.011628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474940/
https://www.ncbi.nlm.nih.gov/pubmed/30819028
http://dx.doi.org/10.1161/JAHA.118.011628

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