Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics

BACKGROUND: The Sigma 1 receptor (Sigmar1) functions as an interorganelle signaling molecule and elicits cytoprotective functions. The presence of Sigmar1 in the heart was first reported on the basis of a ligand‐binding assay, and all studies to date have been limited to pharmacological approaches u...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdullah, Chowdhury S., Alam, Shafiul, Aishwarya, Richa, Miriyala, Sumitra, Panchatcharam, Manikandan, Bhuiyan, Mohammad Alfrad Nobel, Peretik, Jonette M., Orr, A. Wayne, James, Jeanne, Osinska, Hanna, Robbins, Jeffrey, Lorenz, John N., Bhuiyan, Md. Shenuarin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474981/
https://www.ncbi.nlm.nih.gov/pubmed/30371279
http://dx.doi.org/10.1161/JAHA.118.009775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474981/
https://www.ncbi.nlm.nih.gov/pubmed/30371279
http://dx.doi.org/10.1161/JAHA.118.009775

Ejemplares similares