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Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics
BACKGROUND: The Sigma 1 receptor (Sigmar1) functions as an interorganelle signaling molecule and elicits cytoprotective functions. The presence of Sigmar1 in the heart was first reported on the basis of a ligand‐binding assay, and all studies to date have been limited to pharmacological approaches u...
Autores principales: | Abdullah, Chowdhury S., Alam, Shafiul, Aishwarya, Richa, Miriyala, Sumitra, Panchatcharam, Manikandan, Bhuiyan, Mohammad Alfrad Nobel, Peretik, Jonette M., Orr, A. Wayne, James, Jeanne, Osinska, Hanna, Robbins, Jeffrey, Lorenz, John N., Bhuiyan, Md. Shenuarin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474981/ https://www.ncbi.nlm.nih.gov/pubmed/30371279 http://dx.doi.org/10.1161/JAHA.118.009775 |
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