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Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study

BACKGROUND: Malaria exposure in childhood may contribute to high blood pressure (BP) in adults. We used sickle cell trait (SCT) and α(+)thalassemia, genetic variants conferring partial protection against malaria, as tools to test this hypothesis. METHODS AND RESULTS: Study sites were Kilifi, Kenya,...

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Detalles Bibliográficos
Autores principales: Etyang, Anthony O., Kapesa, Sailoki, Odipo, Emily, Bauni, Evasius, Kyobutungi, Catherine, Abdalla, Marwah, Muntner, Paul, Musani, Solomon K., Macharia, Alex, Williams, Thomas N., Cruickshank, J. Kennedy, Smeeth, Liam, Scott, J. Anthony G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475058/
https://www.ncbi.nlm.nih.gov/pubmed/30879408
http://dx.doi.org/10.1161/JAHA.118.011771