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Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study
BACKGROUND: Malaria exposure in childhood may contribute to high blood pressure (BP) in adults. We used sickle cell trait (SCT) and α(+)thalassemia, genetic variants conferring partial protection against malaria, as tools to test this hypothesis. METHODS AND RESULTS: Study sites were Kilifi, Kenya,...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475058/ https://www.ncbi.nlm.nih.gov/pubmed/30879408 http://dx.doi.org/10.1161/JAHA.118.011771 |