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Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study
BACKGROUND: Malaria exposure in childhood may contribute to high blood pressure (BP) in adults. We used sickle cell trait (SCT) and α(+)thalassemia, genetic variants conferring partial protection against malaria, as tools to test this hypothesis. METHODS AND RESULTS: Study sites were Kilifi, Kenya,...
Autores principales: | Etyang, Anthony O., Kapesa, Sailoki, Odipo, Emily, Bauni, Evasius, Kyobutungi, Catherine, Abdalla, Marwah, Muntner, Paul, Musani, Solomon K., Macharia, Alex, Williams, Thomas N., Cruickshank, J. Kennedy, Smeeth, Liam, Scott, J. Anthony G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475058/ https://www.ncbi.nlm.nih.gov/pubmed/30879408 http://dx.doi.org/10.1161/JAHA.118.011771 |
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