Limited AT1 Receptor Internalization Is a Novel Mechanism Underlying Sustained Vasoconstriction Induced by AT1 Receptor Autoantibody From Preeclampsia

BACKGROUND: Angiotensin II type 1 receptor (AT (1)R) autoantibody (AT1‐AA) was first identified as a causative factor in preeclampsia. Unlike physiological ligand angiotensin II (Ang II), AT1‐AA can induce vasoconstriction in a sustained manner, causing a series of adverse effects, such as vascular...

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Detalles Bibliográficos
Autores principales: Bian, Jingwei, Lei, Jinghui, Yin, Xiaochen, Wang, Pengli, Wu, Ye, Yang, Xiaoli, Wang, Li, Zhang, Suli, Liu, Huirong, Fu, Michael L. X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475063/
https://www.ncbi.nlm.nih.gov/pubmed/30845870
http://dx.doi.org/10.1161/JAHA.118.011179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475063/
https://www.ncbi.nlm.nih.gov/pubmed/30845870
http://dx.doi.org/10.1161/JAHA.118.011179

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