Downregulation of survivin by adenovirus-mediated shRNA promotes apoptosis in skin cancer cells

BACKGROUND: Survivin, a member of the inhibitor of apoptosis protein family, is highly expressed in many cancers and has important roles in inhibiting apoptosis by blocking caspase activation. However, its antitumor effects remain largely unknown. Here we explore the function of survivin in skin can...

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Detalles Bibliográficos
Autores principales: Hao, Yuqin, Bai, Xuefeng, Liu, Xia, Kang, Shuxia, Zhang, Xin, Liu, Caiyun, Li, Zhehai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475095/
https://www.ncbi.nlm.nih.gov/pubmed/31118663
http://dx.doi.org/10.2147/OTT.S162150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475095/
https://www.ncbi.nlm.nih.gov/pubmed/31118663
http://dx.doi.org/10.2147/OTT.S162150

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