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Downregulation of survivin by adenovirus-mediated shRNA promotes apoptosis in skin cancer cells
BACKGROUND: Survivin, a member of the inhibitor of apoptosis protein family, is highly expressed in many cancers and has important roles in inhibiting apoptosis by blocking caspase activation. However, its antitumor effects remain largely unknown. Here we explore the function of survivin in skin can...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475095/ https://www.ncbi.nlm.nih.gov/pubmed/31118663 http://dx.doi.org/10.2147/OTT.S162150 |