Validation of Plasmodium falciparum deoxyhypusine synthase as an antimalarial target

BACKGROUND: Hypusination is an essential post-translational modification in eukaryotes. The two enzymes required for this modification, namely deoxyhypusine synthase (DHS) and deoxyhypusine hydrolase are also conserved. Plasmodium falciparum human malaria parasites possess genes for both hypusinatio...

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Detalles Bibliográficos
Autores principales: Aroonsri, Aiyada, Posayapisit, Navaporn, Kongsee, Jindaporn, Siripan, Onsiri, Vitsupakorn, Danoo, Utaida, Sugunya, Uthaipibull, Chairat, Kamchonwongpaisan, Sumalee, Shaw, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475138/
https://www.ncbi.nlm.nih.gov/pubmed/31024761
http://dx.doi.org/10.7717/peerj.6713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475138/
https://www.ncbi.nlm.nih.gov/pubmed/31024761
http://dx.doi.org/10.7717/peerj.6713

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