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Mouse models of Alzheimer’s disease cause rarefaction of pial collaterals and increased severity of ischemic stroke

Vascular dysfunction contributes to the progression and severity of Alzheimer’s disease (AD). Patients with AD also sustain larger infarctions after ischemic stroke; however, the responsible mechanisms are unknown. Pial collaterals are the primary source of protection in stroke. Unfortunately, natur...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Jin, Bo, Faber, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475514/
https://www.ncbi.nlm.nih.gov/pubmed/30519973
http://dx.doi.org/10.1007/s10456-018-9655-0