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rpoB Mutations Causing Discordant Rifampicin Susceptibility in Mycobacterium tuberculosis: Retrospective Analysis of Prevalence, Phenotypic, Genotypic, and Treatment Outcomes
BACKGROUND: Discordant genotypic/phenotypic rifampicin susceptibility testing in Mycobacterium tuberculosis is a significant challenge, yet there are limited data on its prevalence and how best to manage such patients. Whether to treat isolates with rpoB mutations not conferring phenotypic resistanc...
Autores principales: | Mvelase, Nomonde R, Pillay, Melendhran, Sibanda, Wilbert, Ngozo, Jacqueline N, Brust, James C M, Mlisana, Koleka P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475586/ https://www.ncbi.nlm.nih.gov/pubmed/31024968 http://dx.doi.org/10.1093/ofid/ofz065 |
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