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Restoration of Bacterial Microbiome Composition and Diversity Among Treatment Responders in a Phase 2 Trial of RBX2660: An Investigational Microbiome Restoration Therapeutic

BACKGROUND: RBX2660 is an investigational microbiota restoration therapy in phase 3 clinical development for preventing recurrent Clostridioides difficile infections (CDIs). In a randomized, double-blinded placebo-controlled phase 2B trial, RBX2660 was effective at preventing CDI recurrence. The cur...

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Detalles Bibliográficos
Autores principales: Blount, Ken F, Shannon, William D, Deych, Elena, Jones, Courtney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475591/
https://www.ncbi.nlm.nih.gov/pubmed/31024971
http://dx.doi.org/10.1093/ofid/ofz095