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Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations
Several lines of evidence suggest that the primary effect of hypertrophic cardiomyopathy mutations in human β-cardiac myosin is hypercontractility of the heart, which leads to subsequent hypertrophy, fibrosis, and myofilament disarray. Here, I describe three perspectives on the molecular basis of th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475635/ https://www.ncbi.nlm.nih.gov/pubmed/30767072 http://dx.doi.org/10.1007/s00424-019-02259-2 |