Role of co-expressed APOBEC3F and APOBEC3G in inducing HIV-1 drug resistance

The APOBEC3 enzymes can induce mutagenesis of HIV-1 proviral DNA through the deamination of cytosine. HIV-1 overcomes this restriction through the viral protein Vif that induces APOBEC3 proteasomal degradation. Within this dynamic host-pathogen relationship, the APOBEC3 enzymes have been found to be...

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Detalles Bibliográficos
Autores principales: Mohammadzadeh, Nazanin, Love, Robin P., Gibson, Richard, Arts, Eric J., Poon, Art F.Y., Chelico, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475876/
https://www.ncbi.nlm.nih.gov/pubmed/31025011
http://dx.doi.org/10.1016/j.heliyon.2019.e01498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475876/
https://www.ncbi.nlm.nih.gov/pubmed/31025011
http://dx.doi.org/10.1016/j.heliyon.2019.e01498

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