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β1-Adrenoreceptor Polymorphisms and Blood Pressure: 49S Variant Increases Plasma Renin But Not Blood Pressure in Hypertensive Patients

BACKGROUND: Activation of beta-1 adrenoreceptor (β1-AR) in the kidney releases renin that plays a major role in the maintenance of blood pressure. Genetic variation in β1-AR could therefore alter the physiological and clinical effects of this hormone. We tested this hypothesis in patients from a pri...

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Detalles Bibliográficos
Autores principales: Sandilands, Alastair J, O’Shaughnessy, Kevin M, , Yasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475877/
https://www.ncbi.nlm.nih.gov/pubmed/30753253
http://dx.doi.org/10.1093/ajh/hpz019