Investigation of PLGA nanoparticles in conjunction with nuclear localization sequence for enhanced delivery of antimiR phosphorothioates in cancer cells in vitro

Numerous first generation phosphorothioates (PS) and their derivatives have shown promise targeting mRNA for therapeutic applications and also gained market approval for their use as a drug. However, PS have not been explored for targeting microRNAs (miRNAs or miRs). In particular, efficient deliver...

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Detalles Bibliográficos
Autores principales: Malik, Shipra, Bahal, Raman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475967/
https://www.ncbi.nlm.nih.gov/pubmed/31010426
http://dx.doi.org/10.1186/s12951-019-0490-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475967/
https://www.ncbi.nlm.nih.gov/pubmed/31010426
http://dx.doi.org/10.1186/s12951-019-0490-2

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