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Metastable Reprogramming State of Single Transcription Factor-Derived Induced Hepatocyte-Like Cells

We previously described the generation of induced hepatocyte-like cells (iHeps) using the hepatic transcription factor Hnf1a together with small molecules. These iHeps represent a hepatic state that is more mature compared with iHeps generated with multiple hepatic factors. However, the underlying m...

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Detalles Bibliográficos
Autores principales: Hwang, Seon In, Kwak, Tae Hwan, Kang, Ji Hyun, Kim, Jonghun, Lee, Hyunseong, Kim, Kee-Pyo, Ko, Kinarm, Schöler, Hans R., Han, Dong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476006/
https://www.ncbi.nlm.nih.gov/pubmed/31089332
http://dx.doi.org/10.1155/2019/6937257