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A Common Variant of ASAP1 Is Associated with Tuberculosis Susceptibility in the Han Chinese Population

BACKGROUND: ASAP1 (also known as AMAP1 or DDEF1) encodes an Arf GTPase-activating protein (Arf GAP), a multifunctional scaffold protein that induces hydrolysis of GTP bound to the ADP-ribosylation factor (Arf) family GTP-binding proteins. Reduction of ASAP1 expression in vitro was related to suppres...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Zhao, Qi, Shao, Yan, Li, Yan, Song, Honghuan, Li, Guoli, Zhu, Limei, Lu, Wei, Xu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476032/
https://www.ncbi.nlm.nih.gov/pubmed/31089398
http://dx.doi.org/10.1155/2019/7945429