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Protection against HEMA-Induced Mitochondrial Injury In Vitro by Nrf2 Activation

Dental resin monomers such as 2-hydroxyethyl methacrylate (HEMA) disturb vital cell functions and induce mitochondrial intrinsic apoptosis via generation of oxidative stress. Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates the gene expression of antioxidative enzymes and plays a crucial...

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Detalles Bibliográficos
Autores principales: Jiao, Yang, Niu, Tao, Liu, Huan, Tay, Franklin R., Chen, Ji-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476051/
https://www.ncbi.nlm.nih.gov/pubmed/31089407
http://dx.doi.org/10.1155/2019/3501059