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Elevated Platelet Galectin-3 and Rho-Associated Protein Kinase Activity Are Associated with Hemodialysis Arteriovenous Shunt Dysfunction among Subjects with Diabetes Mellitus

INTRODUCTION: Hyperglycemia is a major factor in influencing the patency rate of arteriovenous shunts, potentially associated with the RhoA/Rho-associated protein kinase (ROCK) pathway. Besides, galectin-3 mediates thrombotic mechanisms in venous thrombosis and peripheral artery disease. We hypothes...

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Detalles Bibliográficos
Autores principales: Chen, Po-Wei, Hsu, Ling-Wei, Chang, Hsien-Yuan, Huang, Ting-Chun, Yu, Jia-Rong, Liao, Hsin-Yu, Lee, Cheng-Han, Liu, Ping-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476156/
https://www.ncbi.nlm.nih.gov/pubmed/31080833
http://dx.doi.org/10.1155/2019/8952414