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Mutation of key lysine residues in the Insert B region of the yeast dynamin Vps1 disrupts lipid binding and causes defects in endocytosis

The yeast dynamin-like protein Vps1 has roles at multiple stages of membrane trafficking including Golgi to vacuole transport, endosomal recycling, endocytosis and in peroxisomal fission. While the majority of the Vps1 amino acid sequence shows a high level of identity with the classical mammalian d...

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Detalles Bibliográficos
Autores principales: Smaczynska-de Rooij, Iwona I., Marklew, Christopher J., Palmer, Sarah E., Allwood, Ellen G., Ayscough, Kathryn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476499/
https://www.ncbi.nlm.nih.gov/pubmed/31009484
http://dx.doi.org/10.1371/journal.pone.0215102