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Sulforaphane potentially attenuates arsenic-induced nephrotoxicity via the PI3K/Akt/Nrf2 pathway in albino Wistar rats

Oxidative stress plays a significant role in the pathophysiology of numerous kidney diseases, generally mediated by reactive oxygen species (ROS). Arsenic (Ar) is known to exert its toxicity through the generation of ROS and inflammation. The current study investigates the protective effects of sulf...

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Detalles Bibliográficos
Autores principales: Thangapandiyan, Shanmugam, Ramesh, Mathan, Miltonprabu, Selvaraj, Hema, Tamilselvan, Jothi, Gunasekaran Bavithra, Nandhini, Venkatesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476857/
https://www.ncbi.nlm.nih.gov/pubmed/30835071
http://dx.doi.org/10.1007/s11356-019-04502-w