Additive effects of inhibiting both mTOR and glutamine metabolism on the arthritis in SKG mice

Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated cooperatively in the differentiation and activation of inflammatory immune cells. But the combined inhibition of both pathways was rarely investigated. This study investigated how inhibiting both glutamine meta...

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Detalles Bibliográficos
Autores principales: Ueda, Yo, Saegusa, Jun, Okano, Takaichi, Sendo, Sho, Yamada, Hirotaka, Nishimura, Keisuke, Morinobu, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476881/
https://www.ncbi.nlm.nih.gov/pubmed/31011190
http://dx.doi.org/10.1038/s41598-019-42932-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476881/
https://www.ncbi.nlm.nih.gov/pubmed/31011190
http://dx.doi.org/10.1038/s41598-019-42932-1

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